Illustration featuring a catheter and an anatomical representation of the human cerebrovascular system.

Publications

In recent years, the TNT Lab has published research in a variety of academic journals. Find a featured selection of recent publications below.

 

A Novel Rabbit Thromboembolic Occlusion Model

Ding YH, Fitzgerald S, Liu Y, Dai D, Jakaitis D, Doyle KM, Brinjikji W, Kallmes DF, Savastano LE, Kadirvel R

Journal of NeuroInterventional Surgery. 2021; 13 (11): 1040-1043. doi: 10.1136/neurintsurg-2020-017073.
PubMed Link >

Embolic stroke of undetermined source: The association with carotid intraplaque hemorrhage

Larson A, Nasr DM, Rizvi A, Alzuabi M, Seyedsaadat SM, Lanzino G, Huston J, Lehman VT, Savastano LE, Brinjikji W. https://www.sciencedirect.com/science/article/pii/S1936878X20307245?via=ihub

Cardiovascular Imaging. 2021; 14 (2): 506-508. doi: 10.1016/j.jcmg.2020.08.007.
PubMed Link >

A human brain test bed for research in large vessel occlusion stroke

Gebrezgiabhier D, Liu Y, Reddy AS, Davis E, Zheng Y, Arturo Larco JL, Shih AJ, Pandey AS, Savastano LE

Journal of Neurosurgery. 2021; 135 (4): 1072-1080. doi: 10.3171/2020.7.JNS202278.
PubMed Link >

Standardized fabrication method of human-derived emboli with histologic and mechanical quantification for stroke research

Liu Y, Reddy A, Cockrum J, Ajulufoh MC, Zheng Y, Shih AS, Pandey AS, Savastano LE

Journal of Stroke and Cerebrovascular Diseases. 2020; 29 (11): doi: 10.1016/j.jstrokecerebrovasdis.2020.105205.
PubMed Link >

Standardized fabrication method of human-derived emboli with histologic and mechanical quantification for stroke research

Liu Y, Reddy A, Cockrum J, Ajulufoh MC, Zheng Y, Shih AS, Pandey AS, Savastano LE

Journal of Stroke and Cerebrovascular Diseases. 2020 Nov 1; 29 (11): doi: 10.1016/j.jstrokecerebrovasdis.2020.105205.
PubMed Link >

Symptomatic mild carotid artery stenosis

Larson A, Nardi V, Lanzino G, Brinjikji W, Scharf E, Savastano LE

Contemporary Neurosurgery. 2020 Jul 12; 42 (14): 1-5. doi: 10.1097/01.CNE.0000723688.52449.d5.
PubMed Link >

Carotid intraplaque hemorrhage is associated with cardiovascular risk factors

Larson A, Brinjikji W, Savastano LE, Huston J, Benson JC

Cerebrovascular Diseases. 2020 Jul 12; doi: 10.1159/000508733.
PubMed Link >

Construction of a comprehensive endovascular test bed for research and device development in mechanical thrombectomy in stroke

Reddy A, Liu Y, Cockrum J, Gebrezgiabhier D, Davis E, Zheng Y, Pandey AS, Shih AJ, Savastano LE. Journal of Neurosurgery 2021; doi:10.3171/2020.1.JNS192732.

Journal of Neurosurgery. 2021 Apr 3; 134 (4): 1190–1197. doi: 10.3171/2020.1.JNS192732.
PubMed Link >

Cutting of blood clots – Experiment and smooth particle Galerkin modelling

Liu Y, Zheng Y, Li ADR, Liu Y, Savastano LE, Shih AJ 

CIRP Annals. 2019 Jan 1; 68 (1): 97-100. doi: 10.1016/j.cirp.2019.04.025.
PubMed Link >

Scanning fiber angioscopy: A multimodal intravascular imaging platform for carotid atherosclerosis

Savastano LE, Seibel E

 

Neurosurgery. 2017; 1 (64): 188-198. doi: 10.1093/neuros/nyx322.
PubMed Link >

Multimodal laser-based angioscopy for structural, chemical and biological imaging of atheroscleros

Savastano LE, Zhou Q, Smith A, Vega K, Murga-Zamalloa C, Gordon D, McHugh J, Zhao L, Wang M, Pandey A, Thompson BG, Zu J, Zhang J, Chen, YE, Seibel, EJ, Wang TD

Nature Biomedical Engineering. 2017; doi: 10.1038/s41551-016-0023.
PubMed Link >

Diagnostic and interventional optical angioscopy in ex vivo carotid arteries

Savastano LE, Chaudhary N, Murga-Zamalloa C, Wang M, Wang T., Thompson BG

Operative Neurosurgery. 2017; doi: 10.1093/ons/opw002.
PubMed Link >