Publications

In recent years, the TNT Lab has published research in a variety of academic journals. Find a featured selection of recent publications below.

Innovative Testing Platforms

Failure modes and effects analysis of mechanical thrombectomy for stroke discovered in human brains

Yang Liu, Daniel Gebrezgiabhier, Adithya S Reddy, Evan Davis, Yihao Zheng, Jorge L Arturo Larco, Albert J Shih, Aditya S Pandey, Luis E Savastano

Journal of Neurosurgery. 2021; 136 (204): 197-204. doi: 10.3171/2020.11.JNS203684.

PubMed Link >

Analysis of human emboli and thrombectomy forces in large vessel occlusion stroke

Yang Liu, Yihao Zheng, Adithya S Reddy, Daniel Gebrezgiabhier, Evan Davis, Joshua Cockrum, Joseph J Gemmete, Neeraj Chaudhary, Julius M Griauzde, Aditya S Pandey, Albert J Shih, Luis E Savastano

Journal of Neurosurgery. 2021 Feb 28; 134 (3): 893-901. doi: 10.3171/2019.12.JNS192187.

PubMed Link >

A Novel Rabbit Thromboembolic Occlusion Model

Yong-Hong Ding, Seán Fitzgerald, Yang Liu, Daying Dai, Daniel Jakaitis, Karen Doyle, Waleed Brinjikji, David F Kallmes, Luis Savastano, Ramanathan Kadirvel

Journal of NeuroInterventional Surgery. 2021; 13 (11): 1040-1043. doi: 10.1136/neurintsurg-2020-017073.

PubMed Link >

A human brain test bed for research in large vessel occlusion stroke

Daniel Gebrezgiabhier, Yang Liu, Adithya S Reddy, Evan Davis, Yihao Zheng, Albert J Shih, Aditya S Pandey, Luis E Savastano

Journal of Neurosurgery. 2021; 135 (4): 1072-1080. doi: 10.3171/2020.7.JNS202278.

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Construction of a comprehensive endovascular test bed for research and device development in mechanical thrombectomy in stroke

Adithya S Reddy, Yang Liu, Joshua Cockrum, Daniel Gebrezgiabhier, Evan Davis, Yihao Zheng, Aditya S Pandey, Albert J Shih, Luis E Savastano

Journal of Neurosurgery. 2021 Apr 3; 134 (4): 1190–1197. doi: 10.3171/2020.1.JNS192732.

PubMed Link >

Cutting of blood clots – Experiment and smooth particle Galerkin modelling

Liu Y, Zheng Y, Li ADR, Liu Y, Savastano LE, Shih AJ

CIRP Annals. 2019 Jan 1; 68 (1): 97-100. doi: 10.1016/j.cirp.2019.04.025.

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Deciphering Carotid Plaque Disruption

Embolic stroke of undetermined source: The association with carotid intraplaque hemorrhage

Anthony S Larson, Deena M Nasr, Asim Rizvi, Muayad Alzuabi, Seyed Mohammad Seyedsaadat, Giuseppe Lanzino, John Huston 3rd, Vance T Lehman, Luis E Savastano, Waleed Brinjikji

Cardiovascular Imaging. 2021; 14 (2): 506-508. doi: 10.1016/j.jcmg.2020.08.007.

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Symptomatic mild carotid artery stenosis

Valentina Nardi, John Benson, Melanie C Bois, Luca Saba, Anthony S Larson, Ilke Özcan, Ali Ahmad, David W Morse, Fredric B Meyer, Waleed Brinjikji, Giuseppe Lanzino, Lilach O Lerman, Luis E Savastano, Amir Lerman

Contemporary Neurosurgery. 2020 Jul 12; 42 (14): 1-5. doi: 10.1097/01.CNE.0000723688.52449.d5.

PubMed Link >

Carotid intraplaque hemorrhage is associated with cardiovascular risk factors

Anthony S Larson, Waleed Brinjikji, Luis E Savastano, John Huston Iii, John C Benson

Cerebrovascular Diseases. 2020 Jul 12; doi: 10.1159/000508733.

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Scanning fiber angioscopy: A multimodal intravascular imaging platform for carotid atherosclerosis

Luis E Savastano, Eric J Seibel

Neurosurgery. 2017; 1 (64): 188-198. doi: 10.1093/neuros/nyx322.

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Multimodal laser-based angioscopy for structural, chemical and biological imaging of atheroscleros

Luis E Savastano, Quan Zhou, Arlene Smith, Karla Vega, Carlos Murga-Zamalloa, David Gordon, Jon McHugh, Lili Zhao, Michael Wang, Aditya Pandey, B Gregory Thompson, Jie Xu, Jifeng Zhang, Y Eugene Chen, Eric J Seibel, Thomas D Wang

Nature Biomedical Engineering. 2017; doi: 10.1038/s41551-016-0023.

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Diagnostic and interventional optical angioscopy in ex vivo carotid arteries

Luis E Savastano, Neeraj Chaudhary, Carlos Murga-Zamalloa, Michael Wang, Thomas Wang, B Gregory Thompson

Operative Neurosurgery. 2017; doi: 10.1093/ons/opw002.

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The Science of Mechanical Thrombectomy

Standardized fabrication method of human-derived emboli with histologic and mechanical quantification for stroke research

Yang Liu, Adithya S Reddy, Joshua Cockrum, Miranda C Ajulufoh, Yihao Zheng, Albert J Shih, Aditya S Pandey, Luis E Savastano

Journal of Stroke and Cerebrovascular Diseases. 2020; 29 (11): doi: 10.1016/j.jstrokecerebrovasdis.2020.105205.

PubMed Link >

Standardized fabrication method of human-derived emboli with histologic and mechanical quantification for stroke research

Yang Liu, Adithya S Reddy, Joshua Cockrum, Miranda C Ajulufoh, Yihao Zheng, Albert J Shih, Aditya S Pandey, Luis E Savastano

Journal of Stroke and Cerebrovascular Diseases. 2020 Nov 1; 29 (11): doi: 10.1016/j.jstrokecerebrovasdis.2020.105205.

PubMed Link >